Multiple Routes to Subfunctionalization and Gene Duplicate Specialization

Multiple routes to subfunctionalization and gene duplicate specialization.

Gene duplication is arguably the most significant source of new functional genetic material. A better understanding of the processes that lead to the stable incorporation of gene duplications into the genome is important both because it relates to interspecific differences in genome composition and because it can shed light on why some classes of gene are more prone to duplication than others. ...

The probability of duplicate gene preservation by subfunctionalization.

It has often been argued that gene-duplication events are most commonly followed by a mutational event that silences one member of the pair, while on rare occasions both members of the pair are preserved as one acquires a mutation with a beneficial function and the other retains the original function. However, empirical evidence from genome duplication events suggests that gene duplicates are p...

Rapid subfunctionalization accompanied by prolonged and substantial neofunctionalization in duplicate gene evolution.

Gene duplication is the primary source of new genes. Duplicate genes that are stably preserved in genomes usually have divergent functions. The general rules governing the functional divergence, however, are not well understood and are controversial. The neofunctionalization (NF) hypothesis asserts that after duplication one daughter gene retains the ancestral function while the other acquires ...

Multiple submission, duplicate submission and duplicate publication.

Multiple Routes to Perceptual Learning

A listener’s ability to utilize indexical information in the speech signal can enhance their performance on a variety of speech perception tasks. It is unclear, however, whether such information plays a similar role for spectrally reduced speech signals, such as those experienced by individuals with cochlear implants. The present study compared the effects of training on linguistic versus index...